Bio therapeutics as Novel Technique in Drug Delivery
Biotherapy drug delivery systems use drug molecules made by living organisms naturally or in the laboratory. Fusion proteins, antibodies and therapeutic regenerative enzymes are the main biotherapy agents used. Human insulin is the first biotherapy drug developed through recombinant DNA technology and approved by Eli Lily. This drug has gained popularity in the treatment of cancer, autoimmune diseases, inflammatory diseases, hemophilia, cardiovascular disease, and some genetic disorders. The nature of biotherapy as a new technique in drug delivery has a significant reach. Most bio-therapeutic drugs are recombinant monoclonal antibodies that are produced extensively in mammalian cell lines because of the need for post-translational modifications that are similar or at least similar to those obtained in humans.
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